Dr Lee Kang Hoe graduated from University of Cambridge, UK in 1987. He was a scholar at Jesus College, Cambridge, where he received the Duckworth Prize. Dr Lee has also received a scholarship from the Kuok Foundation, Malaysia, for furthering his medical studies. He performed his surgical housemanship with Professor Sir Roy Calne (one of the pioneers in liver transplantation) at Addenbrooke's Hospital, Cambridge. This was followed by further training in internal medicine at Cambridge and he obtained his MRCP (London) in 1990. Subsequent to this, he joined the Department of Medicine, National University Hospital (NUH), Singapore, and underwent further training in Intensive Care and Respiratory Medicine. This continued with a two-year Critical Care Fellowship at University of Pittsburgh Medical Center, USA – the leading center for liver transplantation in the world – under Professor Thomas Starzl and Professor John Fung, where he was awarded Fellow of the Year. He then returned to Singapore in 1995, and later joined the National University Singapore (NUS) as a Lecturer in the Department of Medicine. He later became an Associate Professor of Medicine and Senior Consultant, and Director of Medical Intensive Care Unit. He was also one of the founding members for the Society of Intensive Care Medicine in Singapore. During this period, he has published many articles on respiratory related issues (especially pneumonia), ICU issues, health outcomes, liver cirrhosis and liver transplantation. He has contributed various book chapters as well, and is the current editor for the Acute Medicine Handbook.

He has lectured in many international, regional, and local meetings on ICU, respiratory, renal, infectious diseases, and transplantation. He has been funded by NMRC, Singapore Cancer Society and industry for his research efforts. Research collaborations are ongoing with NUS investigators including a cross-faculty research programme on decision support which is funded by IDA, and TEC. This is related to collaboration with an NIH decision support group led by Professor Alan Morris at LDS Hospital, Utah, on glucose-insulin computer decision support system. Dr Lee started the liver dialysis programme at NUH and was the lead investigator in a MOH-sponsored programme that subsidized and evaluated the role of MARS^® liver dialysis over a four-year period.

Dr Lee has also been active in medical undergraduate education as part of his role in NUS and was responsible for bringing medical simulation training to the undergraduates and the establishment of a combined NUH-NUS simulation centre using SimMan^®. He is still involved with postgraduate training and is currently a member in the two specialist training committees under the School of Postgraduate Medicine, NUS: Respiratory Medicine and Critical Care Medicine.

Dr Lee joined Gleneagles Hospital in September 2005 as the Director of Critical Care and has been affiliated with The Asian Centre for Liver Diseases and Transplantation (ACLDT) since then. He is still an adjunct Associate Professor at NUS. He has established close contacts with the King's College Liver Unit, UK, as part of the development of ACLDT as a leading liver transplant centre. He is currently responsible for managing all the acute liver failure and liver transplant patients treated at ACLDT. He is also responsible for all liver dialysis treatments and has brought the different liver dialysis devices used at the Liver ICUs at Gleneagles Hospital, making it one of the leading liver dialysis centres in the world.

Awards